Endocrine Surgery

Postoperative hypocalcemia is the most frequent complication after thyroidectomy. One goal of our study was to investigate the parathyroid hormone (PTH) as the main predictor and early postoperative hypocalcemia. The study prospectively included 135 patients who from October 2011 to May 2013 was performed thyroidectomy. According to the results according to logistic regression analysis, postoperative PTH level below 10 pg/ml was the main predictor of postoperative hypocalcemia ( p <0,001). Sensitivity, specificity, positive and negative predictive value of PTH <10 pg / ml for predicting postoperative hypocalcemia were 71%, 99%, 97% and 86%, respectively. It can be concluded that measurement of PTH after 1 hour, and / or on the following day after thyroidectomy hypocalcemia predicts with high sensitivity, specificity. And early detection of PTH allows timely appoint agents calcium and vitamin D to prevent clinical manifestations of postoperative hypoparathyroidism.

The main difficulty of primary hyperparathyroidism in the surgical aspect, it is possible atypical location of the parathyroid glands and multiple nature of the lesion. Proposed significant number of methods for pre- operative and intraoperative for topical diagnosis in primary hyperparathyroidism and the search for new methods and continues to the present. The proposed method of topical diagnostic studies of PTH-FNAB has a high statistical parameters of sensi- tivity, specificity and predictive value. This method is needed as an additional parameter specifying, in the topical diagnosis of primary hyperparathyroidism, especially in the case of ambiguous and questionable data received basic methods of topical studies in primary hyperparathyroidism.